相互作用
Amikacin + Cefadroxil
重症度: 中等度
Amikacin and Cefadroxil: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Aminoglycosides are nephrotoxic and ototoxic, and cephalosporins have been reported to add to renal injury in some cases. Oral cefadroxil has low nephrotoxic potential, so the added risk is generally small.
この相互作用をわかりやすく説明すると
Amikacin and Cefadroxil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amikacin belongs to Anti Bacterial; Cefadroxil belongs to Anti Bacterial.
なぜ起こるのか
Possible additive renal tubular injury; aminoglycoside toxicity is the dominant contributor.
対処法
Monitor serum creatinine and aminoglycoside levels during therapy. Adjust the amikacin dose to renal function.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AmikacinとCefadroxilの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Cefadroxilのその他の相互作用
Amikacinのその他の相互作用
よくある質問
Can I take Amikacin with Cefadroxil?
MediHelp rates the interaction as moderate. Amikacin and Cefadroxil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aminoglycosides are nephrotoxic and ototoxic, and cephalosporins have been reported to add to renal injury in some cases. Oral cefadroxil has low nephrotoxic potential, so the added risk is generally small.
How serious is the interaction between Amikacin and Cefadroxil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and aminoglycoside levels during therapy. Adjust the amikacin dose to renal function.
What other medicines interact with Cefadroxil?
MediHelp also lists interactions of Cefadroxil with, for example, Avelumab, Balstilimab, Bcg vaccine live. The full list is on the Cefadroxil page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
