相互作用
Cefadroxil + Gentamicin
重症度: 中等度
Cefadroxil and Gentamicin: moderate interaction.
最終更新日
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概要
Gentamicin is nephrotoxic and ototoxic, and cephalosporins have occasionally been associated with additional kidney injury when given together. Oral cefadroxil has low nephrotoxic potential, so the added risk is generally small.
この相互作用をわかりやすく説明すると
Cefadroxil and Gentamicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefadroxil belongs to Anti Bacterial; Gentamicin belongs to Anti Bacterial.
なぜ起こるのか
Possible additive renal tubular injury; aminoglycoside toxicity is the dominant contributor.
対処法
Monitor serum creatinine and gentamicin levels during therapy. Adjust the gentamicin dose to renal function.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CefadroxilとGentamicinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Cefadroxilのその他の相互作用
Gentamicinのその他の相互作用
よくある質問
Can I take Cefadroxil with Gentamicin?
MediHelp rates the interaction as moderate. Cefadroxil and Gentamicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Gentamicin is nephrotoxic and ototoxic, and cephalosporins have occasionally been associated with additional kidney injury when given together. Oral cefadroxil has low nephrotoxic potential, so the added risk is generally small.
How serious is the interaction between Cefadroxil and Gentamicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and gentamicin levels during therapy. Adjust the gentamicin dose to renal function.
What other medicines interact with Cefadroxil?
MediHelp also lists interactions of Cefadroxil with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefadroxil page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
