相互作用
Amikacin + Cefiderocol
重症度: 中等度
Amikacin and Cefiderocol: moderate interaction.
最終更新日
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概要
Amikacin can cause kidney injury and ototoxicity, and giving it with a cephalosporin may modestly add to renal risk. Cefiderocol is renally eliminated, so reduced renal function increases its exposure.
この相互作用をわかりやすく説明すると
Amikacin and Cefiderocol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amikacin belongs to Anti Bacterial; Cefiderocol belongs to Anti Bacterial.
なぜ起こるのか
Possible additive nephrotoxicity, not firmly established for cefiderocol.
対処法
Monitor renal function and amikacin trough concentrations, and adjust doses to creatinine clearance.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AmikacinとCefiderocolの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Amikacinのその他の相互作用
Cefiderocolのその他の相互作用
よくある質問
Can I take Amikacin with Cefiderocol?
MediHelp rates the interaction as moderate. Amikacin and Cefiderocol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amikacin can cause kidney injury and ototoxicity, and giving it with a cephalosporin may modestly add to renal risk. Cefiderocol is renally eliminated, so reduced renal function increases its exposure.
How serious is the interaction between Amikacin and Cefiderocol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function and amikacin trough concentrations, and adjust doses to creatinine clearance.
What other medicines interact with Amikacin?
MediHelp also lists interactions of Amikacin with, for example, Cidofovir, Adefovir, Amphotericin b. The full list is on the Amikacin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
