相互作用
Cefiderocol + Warfarin
重症度: 中等度
Cefiderocol and Warfarin: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Antibiotic therapy with cefiderocol may raise INR in patients on warfarin, particularly in acutely ill patients. Direct evidence is limited.
この相互作用をわかりやすく説明すると
Cefiderocol and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefiderocol belongs to Anti Bacterial; Warfarin belongs to Cardiovascular.
なぜ起こるのか
Possible reduction of vitamin K-producing gut flora; the mechanism is not firmly established.
対処法
Check INR within several days of starting cefiderocol and adjust warfarin dose as needed.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CefiderocolとWarfarinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Warfarinのその他の相互作用
Cefiderocolのその他の相互作用
よくある質問
Can I take Cefiderocol with Warfarin?
MediHelp rates the interaction as moderate. Cefiderocol and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Antibiotic therapy with cefiderocol may raise INR in patients on warfarin, particularly in acutely ill patients. Direct evidence is limited.
How serious is the interaction between Cefiderocol and Warfarin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check INR within several days of starting cefiderocol and adjust warfarin dose as needed.
What other medicines interact with Warfarin?
MediHelp also lists interactions of Warfarin with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Warfarin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
