相互作用
Amikacin + Streptomycin
重症度: 重大
Amikacin and Streptomycin: major interaction.
最終更新日
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概要
Using two aminoglycosides together adds to the risk of kidney injury, hearing loss and vestibular damage, and neuromuscular blockade. Toxicity can be permanent.
この相互作用をわかりやすく説明すると
Amikacin and Streptomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amikacin belongs to Anti Bacterial; Streptomycin belongs to Anti Bacterial.
なぜ起こるのか
Additive nephrotoxicity, ototoxicity and neuromuscular blocking effects of aminoglycosides.
対処法
Avoid concurrent use of two aminoglycosides. If unavoidable, monitor renal function, drug levels and audiometry closely.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AmikacinとStreptomycinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Streptomycinのその他の相互作用
Amikacinのその他の相互作用
よくある質問
Can I take Amikacin with Streptomycin?
MediHelp rates the interaction as major. Amikacin and Streptomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Using two aminoglycosides together adds to the risk of kidney injury, hearing loss and vestibular damage, and neuromuscular blockade. Toxicity can be permanent.
How serious is the interaction between Amikacin and Streptomycin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use of two aminoglycosides. If unavoidable, monitor renal function, drug levels and audiometry closely.
What other medicines interact with Streptomycin?
MediHelp also lists interactions of Streptomycin with, for example, Abobotulinumtoxina, Adefovir, Amphotericin b deoxycholate. The full list is on the Streptomycin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
