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相互作用

Bacitracin + Streptomycin

重症度: 重大

Bacitracin and Streptomycin: major interaction.

最終更新日

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概要

Systemic bacitracin is nephrotoxic, and streptomycin can cause both kidney injury and ototoxicity. Together they raise the risk of renal damage and hearing or vestibular injury.

この相互作用をわかりやすく説明すると

Bacitracin and Streptomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Bacitracin belongs to Miscellaneous; Streptomycin belongs to Anti Bacterial.

エビデンスレベル: Moderate

なぜ起こるのか

Additive nephrotoxicity and ototoxicity from two agents that injure renal tubular cells and the inner ear.

対処法

Avoid concurrent use. If unavoidable, monitor serum creatinine, urine output, drug levels and hearing or vestibular function closely.

薬剤師に尋ねること

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、BacitracinとStreptomycinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Bacitracin with Streptomycin?

MediHelp rates the interaction as major. Bacitracin and Streptomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Systemic bacitracin is nephrotoxic, and streptomycin can cause both kidney injury and ototoxicity. Together they raise the risk of renal damage and hearing or vestibular injury.

How serious is the interaction between Bacitracin and Streptomycin?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use. If unavoidable, monitor serum creatinine, urine output, drug levels and hearing or vestibular function closely.

What other medicines interact with Streptomycin?

MediHelp also lists interactions of Streptomycin with, for example, Abobotulinumtoxina, Adefovir, Amikacin. The full list is on the Streptomycin page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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