相互作用
Amoxicillin-clavulanic acid + Eravacycline
重症度: 中等度
Amoxicillin-clavulanic acid and Eravacycline: moderate interaction.
最終更新日
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概要
Eravacycline is a bacteriostatic tetracycline-class antibiotic that could theoretically antagonize beta-lactam killing. Clinical data on this combination are scarce. It matters mainly in severe infections where bactericidal activity is needed.
この相互作用をわかりやすく説明すると
Amoxicillin-clavulanic acid and Eravacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amoxicillin-clavulanic acid belongs to Anti Bacterial; Eravacycline belongs to Anti Bacterial.
なぜ起こるのか
Pharmacodynamic antagonism: growth suppression by a protein synthesis inhibitor reduces beta-lactam bactericidal activity.
対処法
Avoid unnecessary combination and use the narrowest effective regimen. If both are needed, monitor clinical and microbiological response.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Amoxicillin-clavulanic acidとEravacyclineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Amoxicillin-clavulanic acidのその他の相互作用
Eravacyclineのその他の相互作用
よくある質問
Can I take Amoxicillin-clavulanic acid with Eravacycline?
MediHelp rates the interaction as moderate. Amoxicillin-clavulanic acid and Eravacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Eravacycline is a bacteriostatic tetracycline-class antibiotic that could theoretically antagonize beta-lactam killing. Clinical data on this combination are scarce. It matters mainly in severe infections where bactericidal activity is needed.
How serious is the interaction between Amoxicillin-clavulanic acid and Eravacycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid unnecessary combination and use the narrowest effective regimen. If both are needed, monitor clinical and microbiological response.
What other medicines interact with Amoxicillin-clavulanic acid?
MediHelp also lists interactions of Amoxicillin-clavulanic acid with, for example, Methotrexate, Pexidartinib, Pretomanid. The full list is on the Amoxicillin-clavulanic acid page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
