医薬品リファレンス
Eravacycline
Eravacycline is a medicine in the class anti bacterial. It is used for intra-abdominal infections.
- 薬効分類: Anti Bacterial
- 効能・効果: intra-abdominal infections
最終更新日 出典: US FDA label
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要点
- 薬効分類
- Anti Bacterial
- ATCコード
- J01AA13
- 一般的な剤形
- 注射剤
- 既知の相互作用
- 5 (中等度: 5)
- 商品名
- 2
- 国・市場
- 2
何に使われるか
作用のしくみ
Eravacycline is an antibacterial drug (tetracycline class); the label gives no further mechanism detail.
成人の通常用量（添付文書の要約）
Complicated intra-abdominal infection (adults 18 years and older): 1 mg/kg IV infusion over approximately 60 minutes every 12 hours for a total of 4 to 14 days, guided by severity, location and clinical response.
妊娠と授乳
- 妊娠
- Unsafe May cause tooth discoloration and reversible inhibition of bone growth if given in the second and third trimester; limited human data. Tetracyclines can have toxic effects on the developing fetus.
- 授乳
- Unsafe Not known if excreted in human milk; breastfeeding is not recommended during treatment and for 4 days after the last dose.
報告されている副作用
- Infusion site reactions
- Nausea
- Vomiting
- Diarrhea
- Hypotension
- Wound dehiscence
禁忌
- Known hypersensitivity to eravacycline, tetracycline-class antibacterial drugs, or any excipients.
注意が必要な方
- Life-threatening hypersensitivity (anaphylactic) reactions reported; avoid in patients with known tetracycline hypersensitivity and discontinue if an allergic reaction occurs.
- Use during tooth development (last half of pregnancy, infancy, childhood to age 8 years) may cause permanent tooth discoloration and enamel hypoplasia.
- Use during the second and third trimester of pregnancy, infancy and childhood up to age 8 years may cause reversible inhibition of bone growth.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (5)
- Amoxicillin + Eravacycline Moderate
- Amoxicillin-clavulanic acid + Eravacycline Moderate
- Ampicillin + Eravacycline Moderate
- Ampicillin-sulbactam + Eravacycline Moderate
- Eravacycline + Warfarin Moderate
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、Eravacyclineの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- IV preparation and dilution
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同じ分類のほかの薬剤
よくある質問
What is Eravacycline used for?
Eravacycline is a medicine in the class anti bacterial. It is used for Intra-abdominal infections.
What side effects have been reported with Eravacycline?
Infusion site reactions, Nausea, Vomiting, Diarrhea, Hypotension, Wound dehiscence.
Can Eravacycline be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. May cause tooth discoloration and reversible inhibition of bone growth if given in the second and third trimester; limited human data. Tetracyclines can have toxic effects on the developing fetus. Breastfeeding: Unsafe. Not known if excreted in human milk; breastfeeding is not recommended during treatment and for 4 days after the last dose.
What does Eravacycline interact with?
MediHelp lists 5 known interactions for Eravacycline. Moderate: 5. The most serious include Amoxicillin, Amoxicillin-clavulanic acid, Ampicillin.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
