相互作用
Arsenic trioxide + Formoterol
重症度: 重大
Arsenic trioxide and Formoterol: major interaction.
最終更新日
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概要
Arsenic trioxide markedly prolongs the QT interval and can cause torsades de pointes. Formoterol adds QT and hypokalemic effects, which raises arrhythmic risk.
この相互作用をわかりやすく説明すると
Arsenic trioxide and Formoterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Arsenic trioxide belongs to Oncology; Formoterol belongs to Respiratory.
なぜ起こるのか
Additive QT prolongation, with beta-2 agonist hypokalemia increasing susceptibility.
対処法
Avoid if alternatives exist; otherwise obtain baseline and serial ECGs and keep potassium and magnesium in the normal range.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Arsenic trioxideとFormoterolの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Formoterolのその他の相互作用
Arsenic trioxideのその他の相互作用
よくある質問
Can I take Arsenic trioxide with Formoterol?
MediHelp rates the interaction as major. Arsenic trioxide and Formoterol can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Arsenic trioxide markedly prolongs the QT interval and can cause torsades de pointes. Formoterol adds QT and hypokalemic effects, which raises arrhythmic risk.
How serious is the interaction between Arsenic trioxide and Formoterol?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if alternatives exist; otherwise obtain baseline and serial ECGs and keep potassium and magnesium in the normal range.
What other medicines interact with Formoterol?
MediHelp also lists interactions of Formoterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Formoterol page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
