相互作用
Asciminib + Sulphasalazine
重症度: 中等度
Asciminib and Sulphasalazine: moderate interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Asciminib may increase sulfasalazine exposure. This could increase sulfasalazine-related adverse effects.
この相互作用をわかりやすく説明すると
Asciminib and Sulphasalazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Asciminib belongs to Oncology; Sulphasalazine belongs to Gastrointestinal Tract.
なぜ起こるのか
Inhibition of intestinal BCRP efflux increases sulfasalazine absorption.
対処法
Monitor for sulfasalazine adverse effects such as gastrointestinal intolerance and cytopenias. Consider dose reduction if needed.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AsciminibとSulphasalazineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Asciminibのその他の相互作用
Sulphasalazineのその他の相互作用
よくある質問
Can I take Asciminib with Sulphasalazine?
MediHelp rates the interaction as moderate. Asciminib and Sulphasalazine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Asciminib may increase sulfasalazine exposure. This could increase sulfasalazine-related adverse effects.
How serious is the interaction between Asciminib and Sulphasalazine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for sulfasalazine adverse effects such as gastrointestinal intolerance and cytopenias. Consider dose reduction if needed.
What other medicines interact with Asciminib?
MediHelp also lists interactions of Asciminib with, for example, Clarithromycin, Dihydroergotamine, Ergotamine. The full list is on the Asciminib page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
