相互作用
Atorvastatin + Eltrombopag
重症度: 中等度
Atorvastatin and Eltrombopag: moderate interaction.
最終更新日
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概要
Eltrombopag inhibits OATP1B1 and may increase atorvastatin exposure. This raises the risk of statin-related myopathy.
この相互作用をわかりやすく説明すると
Atorvastatin and Eltrombopag can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atorvastatin belongs to Cardiovascular; Eltrombopag belongs to Miscellaneous.
なぜ起こるのか
Inhibition of hepatic OATP1B1 uptake raises systemic statin concentrations.
対処法
Consider a lower atorvastatin dose and monitor for muscle pain, weakness or CK elevation.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AtorvastatinとEltrombopagの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Atorvastatinのその他の相互作用
Eltrombopagのその他の相互作用
よくある質問
Can I take Atorvastatin with Eltrombopag?
MediHelp rates the interaction as moderate. Atorvastatin and Eltrombopag can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Eltrombopag inhibits OATP1B1 and may increase atorvastatin exposure. This raises the risk of statin-related myopathy.
How serious is the interaction between Atorvastatin and Eltrombopag?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider a lower atorvastatin dose and monitor for muscle pain, weakness or CK elevation.
What other medicines interact with Atorvastatin?
MediHelp also lists interactions of Atorvastatin with, for example, Tipranavir, Atazanavir, Clarithromycin. The full list is on the Atorvastatin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
