相互作用
Azathioprine + Bcg vaccine live
重症度: 併用禁忌
Azathioprine and Bcg vaccine live: contraindicated interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
BCG is a live attenuated bacterial vaccine and can cause disseminated BCG infection in immunosuppressed patients. Azathioprine impairs the cellular immunity needed to contain it.
この相互作用をわかりやすく説明すると
Azathioprine and Bcg vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Azathioprine-induced suppression of T-cell function allows uncontrolled replication of live attenuated Mycobacterium bovis.
対処法
Do not give BCG to patients on azathioprine; defer until immunosuppression has been stopped for the interval recommended by local guidance. Assess tuberculosis risk by alternative means.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AzathioprineとBcg vaccine liveの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Azathioprineのその他の相互作用
- Adenovirus types 4 and 7 live + Azathioprine 併用禁忌
- Azathioprine + Febuxostat 併用禁忌
- Azathioprine + Influenza virus vaccine quadrivalent intranasal 併用禁忌
- Azathioprine + Measles mumps and rubella vaccine 併用禁忌
- Azathioprine + Measles mumps and rubella vaccine live 併用禁忌
- Azathioprine + Measles mumps rubella and varicella vaccine live 併用禁忌
よくある質問
Can I take Azathioprine with Bcg vaccine live?
MediHelp rates the interaction as contraindicated. Azathioprine and Bcg vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. BCG is a live attenuated bacterial vaccine and can cause disseminated BCG infection in immunosuppressed patients. Azathioprine impairs the cellular immunity needed to contain it.
How serious is the interaction between Azathioprine and Bcg vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG to patients on azathioprine; defer until immunosuppression has been stopped for the interval recommended by local guidance. Assess tuberculosis risk by alternative means.
What other medicines interact with Azathioprine?
MediHelp also lists interactions of Azathioprine with, for example, Adenovirus types 4 and 7 live, Febuxostat, Influenza virus vaccine quadrivalent intranasal. The full list is on the Azathioprine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
