相互作用
Azathioprine + Influenza virus vaccine quadrivalent intranasal
重症度: 併用禁忌
Azathioprine and Influenza virus vaccine quadrivalent intranasal: contraindicated interaction.
最終更新日
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概要
The intranasal influenza vaccine contains live attenuated virus, which could replicate more extensively in a patient immunosuppressed by azathioprine. This creates a risk of vaccine-strain infection, and the vaccine response may also be reduced.
この相互作用をわかりやすく説明すると
Azathioprine and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Azathioprine-induced impairment of cellular immunity may allow uncontrolled replication of live attenuated virus.
対処法
Do not use the live intranasal vaccine in patients on azathioprine. Give an inactivated injectable influenza vaccine instead.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、AzathioprineとInfluenza virus vaccine quadrivalent intranasalの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Azathioprineのその他の相互作用
よくある質問
Can I take Azathioprine with Influenza virus vaccine quadrivalent intranasal?
MediHelp rates the interaction as contraindicated. Azathioprine and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine contains live attenuated virus, which could replicate more extensively in a patient immunosuppressed by azathioprine. This creates a risk of vaccine-strain infection, and the vaccine response may also be reduced.
How serious is the interaction between Azathioprine and Influenza virus vaccine quadrivalent intranasal?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use the live intranasal vaccine in patients on azathioprine. Give an inactivated injectable influenza vaccine instead.
What other medicines interact with Azathioprine?
MediHelp also lists interactions of Azathioprine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Febuxostat. The full list is on the Azathioprine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
