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相互作用

Azathioprine + Measles mumps and rubella vaccine live

重症度: 併用禁忌

Azathioprine and Measles mumps and rubella vaccine live: contraindicated interaction.

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概要

This live attenuated combination vaccine may cause disseminated infection in patients immunosuppressed by azathioprine. Immune response may also be inadequate.

この相互作用をわかりやすく説明すると

Azathioprine and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

エビデンスレベル: Moderate

なぜ起こるのか

Azathioprine impairs cellular immunity, allowing replication of live attenuated viruses.

対処法

Do not give during azathioprine therapy; vaccinate at least four weeks before starting if possible. Check immunity by serology and use immunoglobulin after exposure.

薬剤師に尋ねること

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+会員向け

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アカウントを作成してPro+トライアルを始めると、AzathioprineとMeasles mumps and rubella vaccine liveの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Azathioprine with Measles mumps and rubella vaccine live?

MediHelp rates the interaction as contraindicated. Azathioprine and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This live attenuated combination vaccine may cause disseminated infection in patients immunosuppressed by azathioprine. Immune response may also be inadequate.

How serious is the interaction between Azathioprine and Measles mumps and rubella vaccine live?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give during azathioprine therapy; vaccinate at least four weeks before starting if possible. Check immunity by serology and use immunoglobulin after exposure.

What other medicines interact with Azathioprine?

MediHelp also lists interactions of Azathioprine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Febuxostat. The full list is on the Azathioprine page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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