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相互作用

Azilsartan-chlorthalidone + Colestipol

重症度: 中等度

Azilsartan-chlorthalidone and Colestipol: moderate interaction.

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概要

Colestipol binds thiazide-type diuretics in the gut and reduces their absorption, which may weaken the diuretic and antihypertensive effect.

この相互作用をわかりやすく説明すると

Azilsartan-chlorthalidone and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Azilsartan-chlorthalidone belongs to Cardiovascular; Colestipol belongs to Cardiovascular.

エビデンスレベル: Moderate

なぜ起こるのか

Anion-exchange resin binds chlorthalidone in the gastrointestinal tract, reducing absorption.

対処法

Give the combination product at least 1 hour before or 4 hours after colestipol, and monitor blood pressure.

薬剤師に尋ねること

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、Azilsartan-chlorthalidoneとColestipolの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Azilsartan-chlorthalidone with Colestipol?

MediHelp rates the interaction as moderate. Azilsartan-chlorthalidone and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Colestipol binds thiazide-type diuretics in the gut and reduces their absorption, which may weaken the diuretic and antihypertensive effect.

How serious is the interaction between Azilsartan-chlorthalidone and Colestipol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give the combination product at least 1 hour before or 4 hours after colestipol, and monitor blood pressure.

What other medicines interact with Azilsartan-chlorthalidone?

MediHelp also lists interactions of Azilsartan-chlorthalidone with, for example, Aliskiren, Sparsentan, Aceclofenac. The full list is on the Azilsartan-chlorthalidone page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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