相互作用
Atenolol-chlorthalidone + Colestipol
重症度: 中等度
Atenolol-chlorthalidone and Colestipol: moderate interaction.
最終更新日
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概要
Colestipol is a bile acid sequestrant that binds to acidic drugs in the gut and can reduce absorption of thiazide-type diuretics. This may weaken the diuretic and antihypertensive effect of chlorthalidone.
この相互作用をわかりやすく説明すると
Atenolol-chlorthalidone and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atenolol-chlorthalidone belongs to Cardiovascular; Colestipol belongs to Cardiovascular.
なぜ起こるのか
Binding of chlorthalidone in the gastrointestinal tract, reducing its absorption.
対処法
Give atenolol-chlorthalidone at least 1 hour before or 4 hours after colestipol. Monitor blood pressure.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、Atenolol-chlorthalidoneとColestipolの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Atenolol-chlorthalidoneのその他の相互作用
Colestipolのその他の相互作用
よくある質問
Can I take Atenolol-chlorthalidone with Colestipol?
MediHelp rates the interaction as moderate. Atenolol-chlorthalidone and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Colestipol is a bile acid sequestrant that binds to acidic drugs in the gut and can reduce absorption of thiazide-type diuretics. This may weaken the diuretic and antihypertensive effect of chlorthalidone.
How serious is the interaction between Atenolol-chlorthalidone and Colestipol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give atenolol-chlorthalidone at least 1 hour before or 4 hours after colestipol. Monitor blood pressure.
What other medicines interact with Atenolol-chlorthalidone?
MediHelp also lists interactions of Atenolol-chlorthalidone with, for example, Acebutolol, Aldesleukin, Amiodarone. The full list is on the Atenolol-chlorthalidone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
