相互作用
Chenodeoxycholic acid + Colestipol
重症度: 中等度
Chenodeoxycholic acid and Colestipol: moderate interaction.
最終更新日
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概要
Colestipol is a bile acid sequestrant that binds bile acids in the intestine. It reduces absorption of chenodeoxycholic acid and may lessen its efficacy.
この相互作用をわかりやすく説明すると
Chenodeoxycholic acid and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chenodeoxycholic acid belongs to Gastrointestinal Tract; Colestipol belongs to Cardiovascular.
なぜ起こるのか
Colestipol binds chenodeoxycholic acid in the gut, preventing absorption and enterohepatic recirculation.
対処法
Give chenodeoxycholic acid at least 2 hours before or after colestipol. Monitor response, or choose an alternative lipid-lowering agent.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Chenodeoxycholic acidとColestipolの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Chenodeoxycholic acidのその他の相互作用
Colestipolのその他の相互作用
よくある質問
Can I take Chenodeoxycholic acid with Colestipol?
MediHelp rates the interaction as moderate. Chenodeoxycholic acid and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Colestipol is a bile acid sequestrant that binds bile acids in the intestine. It reduces absorption of chenodeoxycholic acid and may lessen its efficacy.
How serious is the interaction between Chenodeoxycholic acid and Colestipol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give chenodeoxycholic acid at least 2 hours before or after colestipol. Monitor response, or choose an alternative lipid-lowering agent.
What other medicines interact with Chenodeoxycholic acid?
MediHelp also lists interactions of Chenodeoxycholic acid with, for example, Cyclosporin, Sirolimus, Aluminum hydroxide. The full list is on the Chenodeoxycholic acid page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
