相互作用
Bacitracin + Cisplatin
重症度: 重大
Bacitracin and Cisplatin: major interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Systemic bacitracin (parenteral) is markedly nephrotoxic, and cisplatin is nephrotoxic and ototoxic. Together they raise the risk of acute kidney injury and increased cisplatin exposure.
この相互作用をわかりやすく説明すると
Bacitracin and Cisplatin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bacitracin belongs to Miscellaneous; Cisplatin belongs to Oncology.
なぜ起こるのか
Additive nephrotoxicity from proximal tubular injury.
対処法
Avoid concurrent systemic bacitracin and choose a non-nephrotoxic antibiotic. If unavoidable, monitor serum creatinine and electrolytes closely.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、BacitracinとCisplatinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Cisplatinのその他の相互作用
Bacitracinのその他の相互作用
よくある質問
Can I take Bacitracin with Cisplatin?
MediHelp rates the interaction as major. Bacitracin and Cisplatin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Systemic bacitracin (parenteral) is markedly nephrotoxic, and cisplatin is nephrotoxic and ototoxic. Together they raise the risk of acute kidney injury and increased cisplatin exposure.
How serious is the interaction between Bacitracin and Cisplatin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent systemic bacitracin and choose a non-nephrotoxic antibiotic. If unavoidable, monitor serum creatinine and electrolytes closely.
What other medicines interact with Cisplatin?
MediHelp also lists interactions of Cisplatin with, for example, Cidofovir, Adefovir, Adenovirus types 4 and 7 live. The full list is on the Cisplatin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
