相互作用
Bacitracin + Colistin
重症度: 重大
Bacitracin and Colistin: major interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Systemic bacitracin is markedly nephrotoxic, and combining it with colistin compounds the risk of kidney injury. Neurotoxicity and neuromuscular effects may also be additive.
この相互作用をわかりやすく説明すると
Bacitracin and Colistin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Bacitracin belongs to Miscellaneous; Colistin belongs to Anti Bacterial.
なぜ起こるのか
Additive nephrotoxicity through renal tubular injury.
対処法
Avoid systemic combination; if unavoidable, monitor renal function daily and adjust doses to creatinine clearance.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、BacitracinとColistinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Colistinのその他の相互作用
Bacitracinのその他の相互作用
よくある質問
Can I take Bacitracin with Colistin?
MediHelp rates the interaction as major. Bacitracin and Colistin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Systemic bacitracin is markedly nephrotoxic, and combining it with colistin compounds the risk of kidney injury. Neurotoxicity and neuromuscular effects may also be additive.
How serious is the interaction between Bacitracin and Colistin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid systemic combination; if unavoidable, monitor renal function daily and adjust doses to creatinine clearance.
What other medicines interact with Colistin?
MediHelp also lists interactions of Colistin with, for example, Polymyxin b, Amikacin, Amphotericin b deoxycholate. The full list is on the Colistin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
