相互作用
Baloxavir marboxil + Magnesium sulphate
重症度: 中等度
Baloxavir marboxil and Magnesium sulphate: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Polyvalent cations such as magnesium can chelate baloxavir in the gut and reduce its absorption, which could lower antiviral exposure and weaken influenza treatment or prophylaxis. This is mainly relevant to oral magnesium products, not parenteral magnesium sulfate.
この相互作用をわかりやすく説明すると
Baloxavir marboxil and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Baloxavir marboxil belongs to Anti Virals; Magnesium sulphate belongs to Cardiovascular.
なぜ起こるのか
Chelation of baloxavir by magnesium in the gastrointestinal tract reduces its oral absorption.
対処法
Avoid taking baloxavir together with oral magnesium-containing laxatives, antacids or supplements; if needed, give baloxavir at a different time and consider the product labeling advice on separation. Parenteral magnesium does not need separation.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Baloxavir marboxilとMagnesium sulphateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Magnesium sulphateのその他の相互作用
Baloxavir marboxilのその他の相互作用
よくある質問
Can I take Baloxavir marboxil with Magnesium sulphate?
MediHelp rates the interaction as moderate. Baloxavir marboxil and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Polyvalent cations such as magnesium can chelate baloxavir in the gut and reduce its absorption, which could lower antiviral exposure and weaken influenza treatment or prophylaxis. This is mainly relevant to oral magnesium products, not parenteral magnesium sulfate.
How serious is the interaction between Baloxavir marboxil and Magnesium sulphate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid taking baloxavir together with oral magnesium-containing laxatives, antacids or supplements; if needed, give baloxavir at a different time and consider the product labeling advice on separation. Parenteral magnesium does not need separation.
What other medicines interact with Magnesium sulphate?
MediHelp also lists interactions of Magnesium sulphate with, for example, Amikacin, Amphotericin b deoxycholate, Atracurium. The full list is on the Magnesium sulphate page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
