相互作用
Bcg vaccine live + Fingolimod
重症度: 併用禁忌
Bcg vaccine live and Fingolimod: contraindicated interaction.
最終更新日
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概要
Fingolimod reduces lymphocyte trafficking, so live BCG may replicate uncontrollably and cause disseminated BCG infection. The vaccine response may also be reduced.
この相互作用をわかりやすく説明すると
Bcg vaccine live and Fingolimod are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Fingolimod-induced lymphocyte sequestration impairs immune control of live attenuated bacteria and reduces vaccine response.
対処法
Avoid live vaccines during fingolimod therapy and for about two months after stopping it. Give required live vaccines at least four weeks before starting fingolimod.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Bcg vaccine liveとFingolimodの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Fingolimodのその他の相互作用
よくある質問
Can I take Bcg vaccine live with Fingolimod?
MediHelp rates the interaction as contraindicated. Bcg vaccine live and Fingolimod are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Fingolimod reduces lymphocyte trafficking, so live BCG may replicate uncontrollably and cause disseminated BCG infection. The vaccine response may also be reduced.
How serious is the interaction between Bcg vaccine live and Fingolimod?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during fingolimod therapy and for about two months after stopping it. Give required live vaccines at least four weeks before starting fingolimod.
What other medicines interact with Fingolimod?
MediHelp also lists interactions of Fingolimod with, for example, Adenovirus types 4 and 7 live, Pimozide, Ponesimod. The full list is on the Fingolimod page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
