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相互作用

Fingolimod + Quinidine

重症度: 併用禁忌

Fingolimod and Quinidine: contraindicated interaction.

最終更新日

医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。

このページの臨床コンテンツは英語でのみ提供されています。

概要

Fingolimod labelling excludes patients on class Ia or III antiarrhythmics because of bradycardia and QT risk. Quinidine adds QT prolongation.

この相互作用をわかりやすく説明すると

Fingolimod and Quinidine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Fingolimod belongs to Central Nervous System; Quinidine belongs to Anti Parasitic.

エビデンスレベル: High

なぜ起こるのか

Fingolimod bradycardia plus quinidine QTc prolongation

対処法

Do not combine.

薬剤師に尋ねること

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Pro+会員向け

ページ全体を見る

アカウントを作成してPro+トライアルを始めると、FingolimodとQuinidineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Fingolimod with Quinidine?

MediHelp rates the interaction as contraindicated. Fingolimod and Quinidine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Fingolimod labelling excludes patients on class Ia or III antiarrhythmics because of bradycardia and QT risk. Quinidine adds QT prolongation.

How serious is the interaction between Fingolimod and Quinidine?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine.

What other medicines interact with Quinidine?

MediHelp also lists interactions of Quinidine with, for example, Adagrasib, Arsenic trioxide, Artemether / lumefantrine. The full list is on the Quinidine page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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