相互作用
Bcg vaccine live + Methylprednisolone
重症度: 併用禁忌
Bcg vaccine live and Methylprednisolone: contraindicated interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
BCG is a live attenuated vaccine, and immunosuppressive doses of methylprednisolone can allow uncontrolled replication, causing disseminated BCG infection. The vaccine response may also be diminished.
この相互作用をわかりやすく説明すると
Bcg vaccine live and Methylprednisolone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Corticosteroid-induced impairment of cell-mediated immunity reduces control of live attenuated organisms.
対処法
Do not give BCG to patients on immunosuppressive corticosteroid doses. Delay vaccination until the steroid has been stopped for the interval recommended in local guidance, typically at least one month.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Bcg vaccine liveとMethylprednisoloneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Methylprednisoloneのその他の相互作用
- Measles mumps and rubella vaccine live + Methylprednisolone 併用禁忌
- Measles mumps rubella and varicella vaccine live + Methylprednisolone 併用禁忌
- Measles vaccine + Methylprednisolone 併用禁忌
- Methylprednisolone + Mifepristone 併用禁忌
- Methylprednisolone + Rubella vaccine 併用禁忌
- Methylprednisolone + Smallpox vaccine live 併用禁忌
よくある質問
Can I take Bcg vaccine live with Methylprednisolone?
MediHelp rates the interaction as contraindicated. Bcg vaccine live and Methylprednisolone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. BCG is a live attenuated vaccine, and immunosuppressive doses of methylprednisolone can allow uncontrolled replication, causing disseminated BCG infection. The vaccine response may also be diminished.
How serious is the interaction between Bcg vaccine live and Methylprednisolone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG to patients on immunosuppressive corticosteroid doses. Delay vaccination until the steroid has been stopped for the interval recommended in local guidance, typically at least one month.
What other medicines interact with Methylprednisolone?
MediHelp also lists interactions of Methylprednisolone with, for example, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live, Measles vaccine. The full list is on the Methylprednisolone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
