相互作用
Methylprednisolone + Smallpox vaccine live
重症度: 併用禁忌
Methylprednisolone and Smallpox vaccine live: contraindicated interaction.
最終更新日
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概要
Live vaccinia vaccine can cause progressive vaccinia and generalized infection in immunosuppressed patients, including those on corticosteroids. The vaccine response may also be reduced.
この相互作用をわかりやすく説明すると
Methylprednisolone and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Corticosteroid-induced immunosuppression allows uncontrolled replication of live vaccinia virus.
対処法
Avoid live smallpox vaccine in patients on immunosuppressive steroids outside an emergency. If exposure risk is high, use a non-replicating vaccine where available and obtain specialist advice.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、MethylprednisoloneとSmallpox vaccine liveの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Methylprednisoloneのその他の相互作用
- Bcg vaccine live + Methylprednisolone 併用禁忌
- Measles mumps and rubella vaccine live + Methylprednisolone 併用禁忌
- Measles mumps rubella and varicella vaccine live + Methylprednisolone 併用禁忌
- Measles vaccine + Methylprednisolone 併用禁忌
- Methylprednisolone + Mifepristone 併用禁忌
- Methylprednisolone + Rubella vaccine 併用禁忌
よくある質問
Can I take Methylprednisolone with Smallpox vaccine live?
MediHelp rates the interaction as contraindicated. Methylprednisolone and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live vaccinia vaccine can cause progressive vaccinia and generalized infection in immunosuppressed patients, including those on corticosteroids. The vaccine response may also be reduced.
How serious is the interaction between Methylprednisolone and Smallpox vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live smallpox vaccine in patients on immunosuppressive steroids outside an emergency. If exposure risk is high, use a non-replicating vaccine where available and obtain specialist advice.
What other medicines interact with Methylprednisolone?
MediHelp also lists interactions of Methylprednisolone with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Methylprednisolone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
