相互作用
Bcg vaccine live + Prednisone
重症度: 併用禁忌
Bcg vaccine live and Prednisone: contraindicated interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
BCG is a live attenuated vaccine, and immunosuppressive doses of prednisone may allow disseminated BCG infection and reduce the immune response. Vaccination is generally avoided during high-dose corticosteroid therapy.
この相互作用をわかりやすく説明すると
Bcg vaccine live and Prednisone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Glucocorticoid immunosuppression impairs control of live attenuated organism replication and reduces vaccine response.
対処法
Avoid live BCG during immunosuppressive prednisone therapy and delay vaccination until the drug has been stopped for the interval stated in local guidance (typically at least a month). Low-dose or short-course steroids may be acceptable per guidance.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Bcg vaccine liveとPrednisoneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Prednisoneのその他の相互作用
よくある質問
Can I take Bcg vaccine live with Prednisone?
MediHelp rates the interaction as contraindicated. Bcg vaccine live and Prednisone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. BCG is a live attenuated vaccine, and immunosuppressive doses of prednisone may allow disseminated BCG infection and reduce the immune response. Vaccination is generally avoided during high-dose corticosteroid therapy.
How serious is the interaction between Bcg vaccine live and Prednisone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live BCG during immunosuppressive prednisone therapy and delay vaccination until the drug has been stopped for the interval stated in local guidance (typically at least a month). Low-dose or short-course steroids may be acceptable per guidance.
What other medicines interact with Prednisone?
MediHelp also lists interactions of Prednisone with, for example, Measles vaccine, Mifepristone, Radium-223 dichloride. The full list is on the Prednisone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
