相互作用
Measles vaccine + Prednisone
重症度: 併用禁忌
Measles vaccine and Prednisone: contraindicated interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Measles vaccine is live attenuated, and immunosuppressive doses of prednisone may allow uncontrolled vaccine virus replication and also reduce the immune response. Live vaccination is generally avoided during high-dose steroid therapy.
この相互作用をわかりやすく説明すると
Measles vaccine and Prednisone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Glucocorticoid immunosuppression impairs control of live attenuated virus replication and reduces vaccine response.
対処法
Avoid the live measles vaccine during immunosuppressive prednisone therapy and defer it until the steroid has been stopped for the interval in local guidance (typically at least a month). Low-dose or short-course steroids may be acceptable per guidance.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Measles vaccineとPrednisoneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Prednisoneのその他の相互作用
よくある質問
Can I take Measles vaccine with Prednisone?
MediHelp rates the interaction as contraindicated. Measles vaccine and Prednisone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine is live attenuated, and immunosuppressive doses of prednisone may allow uncontrolled vaccine virus replication and also reduce the immune response. Live vaccination is generally avoided during high-dose steroid therapy.
How serious is the interaction between Measles vaccine and Prednisone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the live measles vaccine during immunosuppressive prednisone therapy and defer it until the steroid has been stopped for the interval in local guidance (typically at least a month). Low-dose or short-course steroids may be acceptable per guidance.
What other medicines interact with Prednisone?
MediHelp also lists interactions of Prednisone with, for example, Bcg vaccine live, Mifepristone, Radium-223 dichloride. The full list is on the Prednisone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
