相互作用
Bedaquiline + Ziprasidone
重症度: 併用禁忌
Bedaquiline and Ziprasidone: contraindicated interaction.
最終更新日
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概要
Both drugs prolong the QT interval. Ziprasidone is contraindicated with other QT-prolonging drugs, and bedaquiline carries a QT warning, so combining them increases the risk of torsades de pointes.
この相互作用をわかりやすく説明すると
Bedaquiline and Ziprasidone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Bedaquiline belongs to Anti Bacterial; Ziprasidone belongs to Central Nervous System.
なぜ起こるのか
Additive QT prolongation.
対処法
Avoid the combination and choose a non-QT-prolonging antipsychotic. If bedaquiline is essential, stop ziprasidone.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、BedaquilineとZiprasidoneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Ziprasidoneのその他の相互作用
Bedaquilineのその他の相互作用
よくある質問
Can I take Bedaquiline with Ziprasidone?
MediHelp rates the interaction as contraindicated. Bedaquiline and Ziprasidone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs prolong the QT interval. Ziprasidone is contraindicated with other QT-prolonging drugs, and bedaquiline carries a QT warning, so combining them increases the risk of torsades de pointes.
How serious is the interaction between Bedaquiline and Ziprasidone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and choose a non-QT-prolonging antipsychotic. If bedaquiline is essential, stop ziprasidone.
What other medicines interact with Ziprasidone?
MediHelp also lists interactions of Ziprasidone with, for example, Amiodarone, Amitriptyline, Arsenic trioxide. The full list is on the Ziprasidone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
