相互作用
Clarithromycin + Ziprasidone
重症度: 併用禁忌
Clarithromycin and Ziprasidone: contraindicated interaction.
最終更新日
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概要
Both drugs prolong the QT interval, and ziprasidone is contraindicated with other QT-prolonging drugs. Combined use raises the risk of torsades de pointes and sudden cardiac death.
この相互作用をわかりやすく説明すると
Clarithromycin and Ziprasidone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Clarithromycin belongs to Anti Bacterial; Ziprasidone belongs to Central Nervous System.
なぜ起こるのか
Additive prolongation of cardiac repolarization (QT interval).
対処法
Avoid the combination and use a non-QT-prolonging antibiotic.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、ClarithromycinとZiprasidoneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Clarithromycinのその他の相互作用
Ziprasidoneのその他の相互作用
よくある質問
Can I take Clarithromycin with Ziprasidone?
MediHelp rates the interaction as contraindicated. Clarithromycin and Ziprasidone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs prolong the QT interval, and ziprasidone is contraindicated with other QT-prolonging drugs. Combined use raises the risk of torsades de pointes and sudden cardiac death.
How serious is the interaction between Clarithromycin and Ziprasidone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use a non-QT-prolonging antibiotic.
What other medicines interact with Clarithromycin?
MediHelp also lists interactions of Clarithromycin with, for example, Astemizole, Avanafil, Cisapride. The full list is on the Clarithromycin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
