相互作用
Benzathine penicillin g + Microbiota
重症度: 中等度
Benzathine penicillin g and Microbiota: moderate interaction.
最終更新日
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概要
Oral microbiota products contain live bacterial spores intended to recolonize the gut. Concurrent penicillin can act against them and reduce engraftment and effectiveness, although benzathine penicillin has a prolonged presence after injection.
この相互作用をわかりやすく説明すると
Benzathine penicillin g and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Antibacterial activity of penicillin against the live microbiota components reduces colonization (pharmacodynamic antagonism).
対処法
Complete antibiotic therapy and wait at least 2 to 4 days before giving oral microbiota. Because benzathine penicillin persists for weeks, consider timing the product with this in mind.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Benzathine penicillin gのその他の相互作用
よくある質問
Can I take Benzathine penicillin g with Microbiota?
MediHelp rates the interaction as moderate. Benzathine penicillin g and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral microbiota products contain live bacterial spores intended to recolonize the gut. Concurrent penicillin can act against them and reduce engraftment and effectiveness, although benzathine penicillin has a prolonged presence after injection.
How serious is the interaction between Benzathine penicillin g and Microbiota?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete antibiotic therapy and wait at least 2 to 4 days before giving oral microbiota. Because benzathine penicillin persists for weeks, consider timing the product with this in mind.
What other medicines interact with Benzathine penicillin g?
MediHelp also lists interactions of Benzathine penicillin g with, for example, Cholera vaccine, Omadacycline, Sodium picosulfate / magnesium oxide / anhydrous citric acid. The full list is on the Benzathine penicillin g page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。