相互作用
Benzathine penicillin g + Omadacycline
重症度: 中等度
Benzathine penicillin g and Omadacycline: moderate interaction.
最終更新日
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概要
Bacteriostatic tetracyclines may blunt the bactericidal effect of penicillins, which require actively growing bacteria. The clinical importance is uncertain and mostly supported by in vitro data and older reports.
この相互作用をわかりやすく説明すると
Benzathine penicillin g and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Benzathine penicillin g belongs to Anti Bacterial; Omadacycline belongs to Anti Bacterial.
なぜ起こるのか
Tetracycline-induced inhibition of bacterial protein synthesis and growth reduces the activity of cell-wall-active beta-lactams.
対処法
Avoid the combination for serious infections where bactericidal activity is needed. If both are required, monitor clinical response.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Benzathine penicillin gとOmadacyclineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Benzathine penicillin gのその他の相互作用
Omadacyclineのその他の相互作用
よくある質問
Can I take Benzathine penicillin g with Omadacycline?
MediHelp rates the interaction as moderate. Benzathine penicillin g and Omadacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bacteriostatic tetracyclines may blunt the bactericidal effect of penicillins, which require actively growing bacteria. The clinical importance is uncertain and mostly supported by in vitro data and older reports.
How serious is the interaction between Benzathine penicillin g and Omadacycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination for serious infections where bactericidal activity is needed. If both are required, monitor clinical response.
What other medicines interact with Benzathine penicillin g?
MediHelp also lists interactions of Benzathine penicillin g with, for example, Cholera vaccine, Microbiota, Sodium picosulfate / magnesium oxide / anhydrous citric acid. The full list is on the Benzathine penicillin g page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
