相互作用
Benzphetamine + Isocarboxazid
重症度: 併用禁忌
Benzphetamine and Isocarboxazid: contraindicated interaction.
最終更新日
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概要
Benzphetamine is a sympathomimetic, and with an MAOI it can provoke severe hypertension and hypertensive crisis. It is contraindicated during and shortly after MAOI therapy.
この相互作用をわかりやすく説明すると
Benzphetamine and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
MAO inhibition leaves norepinephrine stores increased, and the amphetamine-like release of these stores causes an exaggerated pressor response.
対処法
Do not use together or within 14 days of stopping the MAOI. Choose non-pharmacologic or non-stimulant weight management options.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、BenzphetamineとIsocarboxazidの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Isocarboxazidのその他の相互作用
よくある質問
Can I take Benzphetamine with Isocarboxazid?
MediHelp rates the interaction as contraindicated. Benzphetamine and Isocarboxazid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Benzphetamine is a sympathomimetic, and with an MAOI it can provoke severe hypertension and hypertensive crisis. It is contraindicated during and shortly after MAOI therapy.
How serious is the interaction between Benzphetamine and Isocarboxazid?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together or within 14 days of stopping the MAOI. Choose non-pharmacologic or non-stimulant weight management options.
What other medicines interact with Isocarboxazid?
MediHelp also lists interactions of Isocarboxazid with, for example, 5-HTP, Amitriptyline, Amobarbital. The full list is on the Isocarboxazid page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
