相互作用
Bevacizumab + Doxorubicin liposomal
重症度: 中等度
Bevacizumab and Doxorubicin liposomal: moderate interaction.
最終更新日
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概要
Both agents have been associated with cardiac dysfunction, and bevacizumab can cause hypertension and heart failure. Together the risk of cardiomyopathy may be increased.
この相互作用をわかりやすく説明すると
Bevacizumab and Doxorubicin liposomal can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Additive cardiotoxicity from anthracycline myocardial injury and bevacizumab-related hypertension and cardiac dysfunction.
対処法
Assess left ventricular ejection fraction before and during treatment and monitor blood pressure; stop or modify therapy if heart failure develops.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、BevacizumabとDoxorubicin liposomalの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Bevacizumabのその他の相互作用
よくある質問
Can I take Bevacizumab with Doxorubicin liposomal?
MediHelp rates the interaction as moderate. Bevacizumab and Doxorubicin liposomal can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both agents have been associated with cardiac dysfunction, and bevacizumab can cause hypertension and heart failure. Together the risk of cardiomyopathy may be increased.
How serious is the interaction between Bevacizumab and Doxorubicin liposomal?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Assess left ventricular ejection fraction before and during treatment and monitor blood pressure; stop or modify therapy if heart failure develops.
What other medicines interact with Bevacizumab?
MediHelp also lists interactions of Bevacizumab with, for example, Sunitinib, Daunorubicin, Dengue vaccine. The full list is on the Bevacizumab page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
