相互作用
Bexagliflozin + Glimepiride
重症度: 中等度
Bexagliflozin and Glimepiride: moderate interaction.
最終更新日
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概要
Bexagliflozin lowers glucose independently of insulin, and combined with a sulfonylurea it raises the risk of hypoglycemia. The risk is greater with higher sulfonylurea doses.
この相互作用をわかりやすく説明すると
Bexagliflozin and Glimepiride can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bexagliflozin belongs to Endocrine; Glimepiride belongs to Endocrine.
なぜ起こるのか
Additive glucose-lowering effects of SGLT2 inhibition and sulfonylurea-stimulated insulin secretion.
対処法
Consider lowering the glimepiride dose when bexagliflozin is started. Monitor blood glucose and counsel patients on hypoglycemia symptoms.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、BexagliflozinとGlimepirideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Glimepirideのその他の相互作用
Bexagliflozinのその他の相互作用
よくある質問
Can I take Bexagliflozin with Glimepiride?
MediHelp rates the interaction as moderate. Bexagliflozin and Glimepiride can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bexagliflozin lowers glucose independently of insulin, and combined with a sulfonylurea it raises the risk of hypoglycemia. The risk is greater with higher sulfonylurea doses.
How serious is the interaction between Bexagliflozin and Glimepiride?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider lowering the glimepiride dose when bexagliflozin is started. Monitor blood glucose and counsel patients on hypoglycemia symptoms.
What other medicines interact with Glimepiride?
MediHelp also lists interactions of Glimepiride with, for example, Fluconazole, Insulin degludec-liraglutide, Insulin glargine-lixisenatide. The full list is on the Glimepiride page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
