相互作用
Bexagliflozin + Glimepiride-pioglitazone
重症度: 中等度
Bexagliflozin and Glimepiride-pioglitazone: moderate interaction.
最終更新日
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概要
Bexagliflozin lowers glucose through urinary glucose excretion, and this adds to the glucose-lowering effect of the sulfonylurea glimepiride. Together they raise the likelihood of hypoglycemia.
この相互作用をわかりやすく説明すると
Bexagliflozin and Glimepiride-pioglitazone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bexagliflozin belongs to Endocrine; Glimepiride-pioglitazone belongs to Endocrine.
なぜ起こるのか
Additive pharmacodynamic glucose lowering between an SGLT2 inhibitor and an insulin secretagogue.
対処法
Consider lowering the glimepiride dose when starting bexagliflozin and monitor blood glucose. Counsel the patient on recognizing hypoglycemia.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、BexagliflozinとGlimepiride-pioglitazoneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Glimepiride-pioglitazoneのその他の相互作用
Bexagliflozinのその他の相互作用
よくある質問
Can I take Bexagliflozin with Glimepiride-pioglitazone?
MediHelp rates the interaction as moderate. Bexagliflozin and Glimepiride-pioglitazone can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bexagliflozin lowers glucose through urinary glucose excretion, and this adds to the glucose-lowering effect of the sulfonylurea glimepiride. Together they raise the likelihood of hypoglycemia.
How serious is the interaction between Bexagliflozin and Glimepiride-pioglitazone?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider lowering the glimepiride dose when starting bexagliflozin and monitor blood glucose. Counsel the patient on recognizing hypoglycemia.
What other medicines interact with Glimepiride-pioglitazone?
MediHelp also lists interactions of Glimepiride-pioglitazone with, for example, Fluconazole, Gemfibrozil, Insulin aspart. The full list is on the Glimepiride-pioglitazone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
