相互作用
Bictegravir + Magnesium hydroxide
重症度: 中等度
Bictegravir and Magnesium hydroxide: moderate interaction.
最終更新日
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概要
Magnesium-containing antacids bind bictegravir in the gut and lower its absorption, which may reduce antiviral efficacy and risk virologic failure or resistance. The effect depends on the timing of the doses.
この相互作用をわかりやすく説明すると
Bictegravir and Magnesium hydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Divalent magnesium cations chelate the integrase inhibitor in the GI tract, reducing absorption.
対処法
Take bictegravir at least 2 hours before magnesium antacids under fasting conditions. Avoid taking them together or taking the antacid within 2 hours before bictegravir.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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ページ全体を見る
アカウントを作成してPro+トライアルを始めると、BictegravirとMagnesium hydroxideの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Magnesium hydroxideのその他の相互作用
よくある質問
Can I take Bictegravir with Magnesium hydroxide?
MediHelp rates the interaction as moderate. Bictegravir and Magnesium hydroxide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Magnesium-containing antacids bind bictegravir in the gut and lower its absorption, which may reduce antiviral efficacy and risk virologic failure or resistance. The effect depends on the timing of the doses.
How serious is the interaction between Bictegravir and Magnesium hydroxide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take bictegravir at least 2 hours before magnesium antacids under fasting conditions. Avoid taking them together or taking the antacid within 2 hours before bictegravir.
What other medicines interact with Magnesium hydroxide?
MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
