相互作用
Magnesium hydroxide + Ofloxacin
重症度: 重大
Magnesium hydroxide and Ofloxacin: major interaction.
最終更新日
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概要
Magnesium hydroxide chelates ofloxacin in the gut and reduces its absorption, which may result in subtherapeutic levels.
この相互作用をわかりやすく説明すると
Magnesium hydroxide and Ofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Magnesium hydroxide belongs to Gastrointestinal Tract; Ofloxacin belongs to Anti Bacterial.
なぜ起こるのか
Chelation of ofloxacin by magnesium cations in the gastrointestinal tract reduces absorption.
対処法
Give ofloxacin at least 2 hours before or after magnesium hydroxide.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Magnesium hydroxideとOfloxacinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Magnesium hydroxideのその他の相互作用
Ofloxacinのその他の相互作用
よくある質問
Can I take Magnesium hydroxide with Ofloxacin?
MediHelp rates the interaction as major. Magnesium hydroxide and Ofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Magnesium hydroxide chelates ofloxacin in the gut and reduces its absorption, which may result in subtherapeutic levels.
How serious is the interaction between Magnesium hydroxide and Ofloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give ofloxacin at least 2 hours before or after magnesium hydroxide.
What other medicines interact with Magnesium hydroxide?
MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
