医薬品リファレンス
Magnesium hydroxide
Magnesium hydroxide is a medicine in the class gastrointestinal tract. It is used for constipation.
- 薬効分類: Gastrointestinal Tract
- 効能・効果: constipation
最終更新日
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要点
- 薬効分類
- Gastrointestinal Tract
- 一般的な剤形
- 錠剤, 経口懸濁液, 溶液, カプセル剤
- 一般的な規格
- 1200 mg/15 ml, 1200 mg, 400 mg
- 既知の相互作用
- 80 (重大: 7 · 中等度: 28 · 軽度: 45)
- 商品名
- 33
- 国・市場
- 3
何に使われるか
作用のしくみ
Laxative: Promotes osmotic retention of fluid, which distends the colon with increased peristaltic activity and stimulates bowel evacuation. Antacid: Reacts with hydrochloric acid in stomach to form magnesium chloride.
成人の通常用量（添付文書の要約）
Constipation (400 mg/5 mL): 30-60 mL/day PO at bedtime or in divided doses
妊娠と授乳
- 妊娠
- Safe Antacid and laxative (milk of magnesia). Little is absorbed at normal doses; occasional use is acceptable in pregnancy for heartburn or constipation. Avoid long-term high doses, especially with kidney problems.
- 授乳
- Safe A study found no adverse effects in breastfed infants. Oral magnesium barely raises milk levels and the infant absorbs little. LactMed: can be taken while breastfeeding; no special precautions.
報告されている副作用
- Diarrhea
- Abdominal cramping
- Electrolyte imbalance
禁忌
- Renal failure
- Existing electrolyte imbalance
- Appendicitis symptoms or acute surgical abdomen
注意が必要な方
- Contraindicated in Renal failure, Existing electrolyte imbalance, Appendicitis symptoms or acute surgical abdomen, Myocardial damage or heart block.
- Contraindicated in Patients with Fecal impaction or rectal fissures, Intestinal obstruction or perforation, Undiagnosed abdominal pain.
- Use with caution in renal insufficiency.
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (80)
- Ciprofloxacin + Magnesium hydroxide Major
- Dolutegravir + Magnesium hydroxide Major
- Gemifloxacin + Magnesium hydroxide Major
- Levofloxacin + Magnesium hydroxide Major
- Magnesium hydroxide + Moxifloxacin Major
- Magnesium hydroxide + Ofloxacin Major
- Magnesium hydroxide + Raltegravir Major
- Baloxavir marboxil + Magnesium hydroxide Moderate
- Bictegravir + Magnesium hydroxide Moderate
- Cabotegravir + Magnesium hydroxide Moderate
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アカウントを作成してPro+トライアルを始めると、Magnesium hydroxideの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Pharmacokinetics
- Food interactions
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同じ分類のほかの薬剤
よくある質問
What is Magnesium hydroxide used for?
Magnesium hydroxide is a medicine in the class gastrointestinal tract. It is used for Constipation, Heartburn.
What side effects have been reported with Magnesium hydroxide?
Diarrhea, Abdominal cramping, Electrolyte imbalance.
Can Magnesium hydroxide be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Antacid and laxative (milk of magnesia). Little is absorbed at normal doses; occasional use is acceptable in pregnancy for heartburn or constipation. Avoid long-term high doses, especially with kidney problems. Breastfeeding: Safe. A study found no adverse effects in breastfed infants. Oral magnesium barely raises milk levels and the infant absorbs little. LactMed: can be taken while breastfeeding; no special precautions.
What does Magnesium hydroxide interact with?
MediHelp lists 80 known interactions for Magnesium hydroxide. Major: 7 · Moderate: 28 · Minor: 45. The most serious include Ciprofloxacin, Dolutegravir, Gemifloxacin.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
