相互作用
Magnesium hydroxide + Moxifloxacin
重症度: 重大
Magnesium hydroxide and Moxifloxacin: major interaction.
最終更新日 出典: US FDA label
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概要
Magnesium cations bind moxifloxacin in the gut and reduce its absorption, potentially lowering antibiotic effectiveness.
この相互作用をわかりやすく説明すると
Magnesium hydroxide and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Magnesium hydroxide belongs to Gastrointestinal Tract; Moxifloxacin belongs to Anti Bacterial.
なぜ起こるのか
Chelation of moxifloxacin by magnesium cations in the gastrointestinal tract reduces absorption.
対処法
Give moxifloxacin at least 4 hours before or 8 hours after magnesium hydroxide, per labeling.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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アカウントを作成してPro+トライアルを始めると、Magnesium hydroxideとMoxifloxacinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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参考文献
Magnesium hydroxideのその他の相互作用
Moxifloxacinのその他の相互作用
よくある質問
Can I take Magnesium hydroxide with Moxifloxacin?
MediHelp rates the interaction as major. Magnesium hydroxide and Moxifloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Magnesium cations bind moxifloxacin in the gut and reduce its absorption, potentially lowering antibiotic effectiveness.
How serious is the interaction between Magnesium hydroxide and Moxifloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give moxifloxacin at least 4 hours before or 8 hours after magnesium hydroxide, per labeling.
What other medicines interact with Magnesium hydroxide?
MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
