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相互作用

Bosutinib + Desloratadine

重症度: 軽度

Bosutinib and Desloratadine: minor interaction.

最終更新日

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概要

Bosutinib inhibits P-glycoprotein and may modestly increase desloratadine exposure. The clinical consequence is probably small given desloratadine's broad safety margin.

この相互作用をわかりやすく説明すると

Bosutinib and Desloratadine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Bosutinib belongs to Oncology; Desloratadine belongs to Respiratory.

エビデンスレベル: Low

なぜ起こるのか

P-glycoprotein inhibition by bosutinib reducing desloratadine efflux.

対処法

No dose adjustment is usually required; monitor for increased antihistamine adverse effects.

薬剤師に尋ねること

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、BosutinibとDesloratadineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Bosutinib with Desloratadine?

MediHelp rates the interaction as minor. Bosutinib and Desloratadine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Bosutinib inhibits P-glycoprotein and may modestly increase desloratadine exposure. The clinical consequence is probably small given desloratadine's broad safety margin.

How serious is the interaction between Bosutinib and Desloratadine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No dose adjustment is usually required; monitor for increased antihistamine adverse effects.

What other medicines interact with Desloratadine?

MediHelp also lists interactions of Desloratadine with, for example, Erdafitinib, Isocarboxazid, Tranylcypromine. The full list is on the Desloratadine page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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