相互作用
Cefaclor + Cholera vaccine
重症度: 中等度
Cefaclor and Cholera vaccine: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
The oral live attenuated cholera vaccine relies on replication of the vaccine strain in the gut. Systemic antibiotics may be active against the strain and reduce the immune response. Cefaclor activity against Vibrio cholerae is uncertain, but labeling advises caution with antibiotics in general.
この相互作用をわかりやすく説明すると
Cefaclor and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Antibacterial activity may inhibit replication of the live attenuated vaccine strain, lowering immunogenicity.
対処法
Avoid giving the vaccine to patients who have taken systemic antibiotics in the previous 14 days. Delay vaccination until the antibiotic course is complete and the interval has passed.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CefaclorとCholera vaccineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Cefaclorのその他の相互作用
よくある質問
Can I take Cefaclor with Cholera vaccine?
MediHelp rates the interaction as moderate. Cefaclor and Cholera vaccine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. The oral live attenuated cholera vaccine relies on replication of the vaccine strain in the gut. Systemic antibiotics may be active against the strain and reduce the immune response. Cefaclor activity against Vibrio cholerae is uncertain, but labeling advises caution with antibiotics in general.
How serious is the interaction between Cefaclor and Cholera vaccine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving the vaccine to patients who have taken systemic antibiotics in the previous 14 days. Delay vaccination until the antibiotic course is complete and the interval has passed.
What other medicines interact with Cefaclor?
MediHelp also lists interactions of Cefaclor with, for example, Bcg vaccine live, Kanamycin, Microbiota. The full list is on the Cefaclor page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
