相互作用
Cefaclor + Sodium picosulfate / magnesium oxide / anhydrous citric acid
重症度: 中等度
Cefaclor and Sodium picosulfate / magnesium oxide / anhydrous citric acid: moderate interaction.
最終更新日
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概要
Sodium picosulfate is a prodrug that needs colonic bacteria to form its active laxative metabolite. Antibiotics given before bowel preparation may reduce this conversion and result in inadequate bowel cleansing before colonoscopy.
この相互作用をわかりやすく説明すると
Cefaclor and Sodium picosulfate / magnesium oxide / anhydrous citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Antibiotic suppression of colonic bacteria that convert sodium picosulfate to its active metabolite.
対処法
Where possible, avoid starting the antibiotic before the preparation, or complete the course earlier. Confirm adequate bowel cleansing before the procedure.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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アカウントを作成してPro+トライアルを始めると、CefaclorとSodium picosulfate / magnesium oxide / anhydrous citric acidの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Cefaclorのその他の相互作用
よくある質問
Can I take Cefaclor with Sodium picosulfate / magnesium oxide / anhydrous citric acid?
MediHelp rates the interaction as moderate. Cefaclor and Sodium picosulfate / magnesium oxide / anhydrous citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium picosulfate is a prodrug that needs colonic bacteria to form its active laxative metabolite. Antibiotics given before bowel preparation may reduce this conversion and result in inadequate bowel cleansing before colonoscopy.
How serious is the interaction between Cefaclor and Sodium picosulfate / magnesium oxide / anhydrous citric acid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Where possible, avoid starting the antibiotic before the preparation, or complete the course earlier. Confirm adequate bowel cleansing before the procedure.
What other medicines interact with Cefaclor?
MediHelp also lists interactions of Cefaclor with, for example, Bcg vaccine live, Cholera vaccine, Kanamycin. The full list is on the Cefaclor page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
