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相互作用

Cefaclor + Microbiota

重症度: 中等度

Cefaclor and Microbiota: moderate interaction.

最終更新日

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このページの臨床コンテンツは英語でのみ提供されています。

概要

Oral fecal microbiota products contain live bacterial spores intended to recolonize the gut. A systemic cephalosporin that is still present may reduce the viability or engraftment of these organisms and weaken the preventive effect against recurrent C. difficile infection.

この相互作用をわかりやすく説明すると

Cefaclor and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

エビデンスレベル: Low

なぜ起こるのか

Antibacterial activity against the live bacterial components of the product reduces colonization (pharmacodynamic antagonism).

対処法

Finish the antibiotic course and allow a washout interval of a few days before starting the microbiota product, as the labeling advises. Do not give the product during active cephalosporin therapy.

薬剤師に尋ねること

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、CefaclorとMicrobiotaの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Cefaclor with Microbiota?

MediHelp rates the interaction as moderate. Cefaclor and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral fecal microbiota products contain live bacterial spores intended to recolonize the gut. A systemic cephalosporin that is still present may reduce the viability or engraftment of these organisms and weaken the preventive effect against recurrent C. difficile infection.

How serious is the interaction between Cefaclor and Microbiota?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Finish the antibiotic course and allow a washout interval of a few days before starting the microbiota product, as the labeling advises. Do not give the product during active cephalosporin therapy.

What other medicines interact with Cefaclor?

MediHelp also lists interactions of Cefaclor with, for example, Bcg vaccine live, Cholera vaccine, Kanamycin. The full list is on the Cefaclor page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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