相互作用
Cefadroxil + Mycophenolate
重症度: 中等度
Cefadroxil and Mycophenolate: moderate interaction.
最終更新日
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概要
Some antibiotics, including cephalosporins, have been associated with lower mycophenolic acid exposure, probably by reducing gut bacteria that deconjugate the glucuronide and allow its reabsorption. The legacy renal competition explanation is not well supported. Reduced exposure could weaken immunosuppression.
この相互作用をわかりやすく説明すると
Cefadroxil and Mycophenolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Probable reduction of enterohepatic recirculation of mycophenolic acid glucuronide due to gut flora changes.
対処法
Watch for signs of graft rejection or reduced immunosuppression during and after the antibiotic course. Consider mycophenolic acid level monitoring where available.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CefadroxilとMycophenolateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Cefadroxilのその他の相互作用
よくある質問
Can I take Cefadroxil with Mycophenolate?
MediHelp rates the interaction as moderate. Cefadroxil and Mycophenolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Some antibiotics, including cephalosporins, have been associated with lower mycophenolic acid exposure, probably by reducing gut bacteria that deconjugate the glucuronide and allow its reabsorption. The legacy renal competition explanation is not well supported. Reduced exposure could weaken immunosuppression.
How serious is the interaction between Cefadroxil and Mycophenolate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Watch for signs of graft rejection or reduced immunosuppression during and after the antibiotic course. Consider mycophenolic acid level monitoring where available.
What other medicines interact with Cefadroxil?
MediHelp also lists interactions of Cefadroxil with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefadroxil page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
