相互作用
Cefditoren + Plazomicin
重症度: 中等度
Cefditoren and Plazomicin: moderate interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Plazomicin is an aminoglycoside with significant nephrotoxicity, ototoxicity and neuromuscular blockade risk. Concurrent cephalosporins have been linked to additive renal injury in some cases.
この相互作用をわかりやすく説明すると
Cefditoren and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefditoren belongs to Anti Bacterial; Plazomicin belongs to Anti Bacterial.
なぜ起こるのか
Possible additive nephrotoxicity; the aminoglycoside itself causes proximal tubular and cochlear toxicity.
対処法
Monitor serum creatinine and plazomicin trough levels, and adjust dosing for renal function.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CefditorenとPlazomicinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Cefditorenのその他の相互作用
Plazomicinのその他の相互作用
よくある質問
Can I take Cefditoren with Plazomicin?
MediHelp rates the interaction as moderate. Cefditoren and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Plazomicin is an aminoglycoside with significant nephrotoxicity, ototoxicity and neuromuscular blockade risk. Concurrent cephalosporins have been linked to additive renal injury in some cases.
How serious is the interaction between Cefditoren and Plazomicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and plazomicin trough levels, and adjust dosing for renal function.
What other medicines interact with Cefditoren?
MediHelp also lists interactions of Cefditoren with, for example, Aluminum hydroxide, Calcium carbonate, Calcium. The full list is on the Cefditoren page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
