Drug interactions
Cefditoren + Plazomicin
Severity: Moderate
Cefditoren and Plazomicin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Plazomicin is an aminoglycoside with significant nephrotoxicity, ototoxicity and neuromuscular blockade risk. Concurrent cephalosporins have been linked to additive renal injury in some cases.
What this interaction means in plain words
Cefditoren and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefditoren belongs to Anti Bacterial; Plazomicin belongs to Anti Bacterial.
Why it happens
Possible additive nephrotoxicity; the aminoglycoside itself causes proximal tubular and cochlear toxicity.
What to do
Monitor serum creatinine and plazomicin trough levels, and adjust dosing for renal function.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Cefditoren
- Aluminum hydroxide + Cefditoren Moderate
- Calcium carbonate + Cefditoren Moderate
- Calcium + Cefditoren Moderate
- Cefditoren + Cholera vaccine Moderate
- Cefditoren + Cimetidine Moderate
- Cefditoren + Dexlansoprazole Moderate
Other interactions of Plazomicin
- Cefaclor + Plazomicin Moderate
- Cefadroxil + Plazomicin Moderate
- Cefalexin + Plazomicin Moderate
- Cefazolin + Plazomicin Moderate
- Cefepime + Plazomicin Moderate
- Cefixime + Plazomicin Moderate
Frequently asked questions
Can I take Cefditoren with Plazomicin?
MediHelp rates the interaction as moderate. Cefditoren and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Plazomicin is an aminoglycoside with significant nephrotoxicity, ototoxicity and neuromuscular blockade risk. Concurrent cephalosporins have been linked to additive renal injury in some cases.
How serious is the interaction between Cefditoren and Plazomicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and plazomicin trough levels, and adjust dosing for renal function.
What other medicines interact with Cefditoren?
MediHelp also lists interactions of Cefditoren with, for example, Aluminum hydroxide, Calcium carbonate, Calcium. The full list is on the Cefditoren page.
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