相互作用
Cefazolin + Plazomicin
重症度: 中等度
Cefazolin and Plazomicin: moderate interaction.
最終更新日
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概要
Cefazolin given with plazomicin may add to the risk of kidney injury, and plazomicin carries its own risk of nephrotoxicity, ototoxicity and neuromuscular blockade. Impaired renal function would increase plazomicin exposure and toxicity.
この相互作用をわかりやすく説明すると
Cefazolin and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefazolin belongs to Anti Bacterial; Plazomicin belongs to Anti Bacterial.
なぜ起こるのか
Additive nephrotoxic potential, with reduced aminoglycoside clearance if renal function declines.
対処法
Monitor serum creatinine and plazomicin concentrations during combined use. Adjust the plazomicin dose to renal function and monitor for hearing or balance changes.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CefazolinとPlazomicinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Cefazolinのその他の相互作用
Plazomicinのその他の相互作用
よくある質問
Can I take Cefazolin with Plazomicin?
MediHelp rates the interaction as moderate. Cefazolin and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefazolin given with plazomicin may add to the risk of kidney injury, and plazomicin carries its own risk of nephrotoxicity, ototoxicity and neuromuscular blockade. Impaired renal function would increase plazomicin exposure and toxicity.
How serious is the interaction between Cefazolin and Plazomicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and plazomicin concentrations during combined use. Adjust the plazomicin dose to renal function and monitor for hearing or balance changes.
What other medicines interact with Cefazolin?
MediHelp also lists interactions of Cefazolin with, for example, Amikacin, Bcg vaccine live, Cholera vaccine. The full list is on the Cefazolin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
