相互作用
Cephaloridine + Vancomycin
重症度: 重大
Cephaloridine and Vancomycin: major interaction.
最終更新日
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概要
Cephaloridine is a markedly nephrotoxic cephalosporin, and combining it with vancomycin may increase the risk of kidney injury. Cephaloridine is obsolete and rarely available.
この相互作用をわかりやすく説明すると
Cephaloridine and Vancomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
なぜ起こるのか
Additive nephrotoxicity, with cephaloridine causing proximal tubular injury.
対処法
Avoid the combination and choose a less nephrotoxic alternative; if used, monitor serum creatinine and urine output closely.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CephaloridineとVancomycinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Vancomycinのその他の相互作用
よくある質問
Can I take Cephaloridine with Vancomycin?
MediHelp rates the interaction as major. Cephaloridine and Vancomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cephaloridine is a markedly nephrotoxic cephalosporin, and combining it with vancomycin may increase the risk of kidney injury. Cephaloridine is obsolete and rarely available.
How serious is the interaction between Cephaloridine and Vancomycin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and choose a less nephrotoxic alternative; if used, monitor serum creatinine and urine output closely.
What other medicines interact with Vancomycin?
MediHelp also lists interactions of Vancomycin with, for example, Amikacin, Bacitracin, Capreomycin. The full list is on the Vancomycin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
