相互作用
Charcoal + Citalopram
重症度: 中等度
Charcoal and Citalopram: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Activated charcoal binds citalopram in the gut and reduces its absorption. With therapeutic dosing this could lower efficacy, whereas in overdose this effect is intentionally used to limit toxicity.
この相互作用をわかりやすく説明すると
Charcoal and Citalopram can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Charcoal belongs to Gastrointestinal Tract; Citalopram belongs to Central Nervous System.
なぜ起こるのか
Charcoal adsorbs citalopram in the gastrointestinal tract, reducing its absorption.
対処法
Separate therapeutic citalopram doses from charcoal by at least 2 hours, ideally giving citalopram well before charcoal. In overdose, give charcoal as indicated and monitor ECG and for serotonin toxicity.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CharcoalとCitalopramの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Charcoalのその他の相互作用
Citalopramのその他の相互作用
よくある質問
Can I take Charcoal with Citalopram?
MediHelp rates the interaction as moderate. Charcoal and Citalopram can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Activated charcoal binds citalopram in the gut and reduces its absorption. With therapeutic dosing this could lower efficacy, whereas in overdose this effect is intentionally used to limit toxicity.
How serious is the interaction between Charcoal and Citalopram?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate therapeutic citalopram doses from charcoal by at least 2 hours, ideally giving citalopram well before charcoal. In overdose, give charcoal as indicated and monitor ECG and for serotonin toxicity.
What other medicines interact with Charcoal?
MediHelp also lists interactions of Charcoal with, for example, Digoxin, Leflunomide, Methotrexate. The full list is on the Charcoal page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
