相互作用
Cilostazol + Dalteparin
重症度: 重大
Cilostazol and Dalteparin: major interaction.
最終更新日
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概要
Cilostazol inhibits platelet aggregation, and dalteparin is an anticoagulant, so haemostasis is impaired at two steps. The risk of bleeding is increased, including gastrointestinal and intracranial haemorrhage.
この相互作用をわかりやすく説明すると
Cilostazol and Dalteparin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cilostazol belongs to Cardiovascular; Dalteparin belongs to Cardiovascular.
なぜ起こるのか
Additive impairment of haemostasis: PDE3-mediated antiplatelet effect plus anticoagulation
対処法
Combine only when clearly indicated; monitor haemoglobin and for bleeding, and review concurrent antiplatelet or NSAID use.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CilostazolとDalteparinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Dalteparinのその他の相互作用
Cilostazolのその他の相互作用
よくある質問
Can I take Cilostazol with Dalteparin?
MediHelp rates the interaction as major. Cilostazol and Dalteparin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cilostazol inhibits platelet aggregation, and dalteparin is an anticoagulant, so haemostasis is impaired at two steps. The risk of bleeding is increased, including gastrointestinal and intracranial haemorrhage.
How serious is the interaction between Cilostazol and Dalteparin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Combine only when clearly indicated; monitor haemoglobin and for bleeding, and review concurrent antiplatelet or NSAID use.
What other medicines interact with Dalteparin?
MediHelp also lists interactions of Dalteparin with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dalteparin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
