相互作用
Dalteparin + Ketorolac
重症度: 併用禁忌
Dalteparin and Ketorolac: contraindicated interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Ketorolac impairs platelet function and can cause GI bleeding, and dalteparin is an anticoagulant, so serious hemorrhage risk increases, including spinal or epidural hematoma around neuraxial procedures. Ketorolac labeling contraindicates use in patients at risk of bleeding.
この相互作用をわかりやすく説明すると
Dalteparin and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dalteparin belongs to Cardiovascular; Ketorolac belongs to Musculoskeletal.
なぜ起こるのか
Additive hemostatic impairment through antiplatelet NSAID effect and factor Xa inhibition by low molecular weight heparin.
対処法
Avoid ketorolac in patients on dalteparin and select a non-NSAID analgesic; if exposure occurs, monitor for bleeding signs and hemoglobin.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DalteparinとKetorolacの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Ketorolacのその他の相互作用
Dalteparinのその他の相互作用
よくある質問
Can I take Dalteparin with Ketorolac?
MediHelp rates the interaction as contraindicated. Dalteparin and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ketorolac impairs platelet function and can cause GI bleeding, and dalteparin is an anticoagulant, so serious hemorrhage risk increases, including spinal or epidural hematoma around neuraxial procedures. Ketorolac labeling contraindicates use in patients at risk of bleeding.
How serious is the interaction between Dalteparin and Ketorolac?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid ketorolac in patients on dalteparin and select a non-NSAID analgesic; if exposure occurs, monitor for bleeding signs and hemoglobin.
What other medicines interact with Ketorolac?
MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
